Hypersensitivity to the components of the formula; elderly or children under 12-16 years; patients with pulmonary hypertension or severe hypertension; history of cardiovascular or cerebrovascular
psychiatric disorders, including anorexia nervosa and depression; history or predisposition to drug and alcohol use; advanced atherosclerosis; hyperthyroidism; known hypersensitivity or idiosyncrasy to sympathomimetic amines; prostatic hypertrophy or any obstructive condition of the urinary tract; closed angle glaucoma; states of agitation;
Warnings and precautions
Strict medical control; cardiovascular and cerebrovascular accidents, often after rapid weight loss. In obese patients at risk of enf. vascular care should be taken to ensure gradual and controlled weight loss; patients with a history of enf. cerebrovascular or cardiovascular; sympathomimetic amines lose anorexigenic power after several weeks of tto; epileptic patients
Adm. 15 days after interrupting a treatment with an MAOI, hypertensive crises could occur; tricyclic antidepressants and serotonin reuptake inhibitors such as venlafaxine and citalopram by increasing the risk of presenting serotonergic syndrome; guanetidine or its derivatives by sharing the same place of action and guanetidine and its derivatives could be displaced by decreasing their antihypertensive effect; Phenylethylamine derivatives, appetite suppressants such as sibutramine and tricyclic antidepressants, as it may potentiate the effects on blood pressure of the latter; Sympathomimetic and anesthetic agents in general can cause arrhythmias.
Lab: positive reaction in antidoping tests
Insufficient clinical experience.
Given the insufficient clinical experience its use is not recommended
Clobenzorex adverse reactions
Pulmonary hypertension; drug tolerance, dependence and withdrawal syndrome; psychotic reactions or psychosis, depression, nervousness, agitation, sleep disorders and vertigo; tachycardia, palpitations, high blood pressure and chest pain; dry mouth and constipation; dysuria and urinary retention
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